Red blood cell volume in preterm neonates

Journal Article · Thu Oct 01 00:00:00 EDT 1981 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198110000-00006· OSTI ID:5503553

Quaife, M A; Dirksen, J W; Paxson, Jr, C L; McIntire, Jr, R H

In the high-risk neonate, the direct determination of the red cell volume by radionuclide dilution technique appears to be the singularly definitive method of defining treatment efficacy, and is thus a useful evaluation and management tool for the pediatrician. For effective patient management, the red blood cell(RBC) volume of 69 preterm and term neonates was determined. The method utilized, Tc-99m-labeled RBCs, provided a fast and accurate answer with a large reduction in the absorbed radiation dose. In the population studied within a high-risk newborn ICU, the mean RBC volumes between the preterm and term neonates were without significant difference. Grouping and analysis of the RBC volume data with respect to birth weight, gestational ages, and 1- and 5-minute Apgar scores revealed on statistical difference. The mean value found in our population, 32.2 +/- 9.2 ml/kg, however, does differ from those previously reported in which the determinations were made using an indirect estimation from the plasma compartment.

• Research Organization: University of Nebraska Medical Center, Omaha
• OSTI ID: 5503553
• Journal Information: Clin. Nucl. Med.; (United States), Vol. 6:10
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
HEMIC DISEASES
DIAGNOSIS
TECHNETIUM 99
DIAGNOSTIC USES
BLOOD PLASMA
ERYTHROCYTES
INFANTS
ISOMERIC NUCLEI
ISOTOPE DILUTION
LABELLED COMPOUNDS
PATIENTS
PEDIATRICS
RADIATION DOSES
VOLUME
AGE GROUPS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CHILDREN
DISEASES
DOSES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MATERIALS
MEDICINE
NUCLEI
ODD-EVEN NUCLEI
RADIOISOTOPES
TECHNETIUM ISOTOPES
TRACER TECHNIQUES
USES
YEARS LIVING RADIOISOTOPES
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560171 - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987)
550901 - Pathology- Tracer Techniques