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Title: In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes

Journal Article · · Am. J. Vet. Res.; (United States)
OSTI ID:5502689

Porcine carrier erythrocyte survival was measured in adult pigs. (14C)Sucrose-loaded erythrocytes had a biphasic survival curve, with as much as 50% of the cells removed from circulation in the first 24 hours. The remaining cells had a 35-day half-life. Encapsulation values were measured for porcine erythrocytes and entrapment of (14C)sucrose was greater than 45%. Addition of inosine and glucose to the dialyzed cells and to the final wash buffer before reinjection of autologous cells did not improve their survival.

Research Organization:
Veterinary Toxicology and Entomology Research Laboratory, US Department of Agriculture, College Station, TX
OSTI ID:
5502689
Journal Information:
Am. J. Vet. Res.; (United States), Vol. 44:6
Country of Publication:
United States
Language:
English