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Title: Bioconcentration factors and lipid solubility

Journal Article · · Environmental Science and Technology; (USA)
DOI:https://doi.org/10.1021/es00015a024· OSTI ID:5477424
 [1];  [2]
  1. Institute of Paper Science and Technology, Atlanta, GA (USA)
  2. U.S. Environmental Protection Agency, Athens, GA (USA)

The log-log relationship between bioconcentration and hydrophobicity breaks down for several medium and high molecular weight solutes that bioconcentrate either to a small extent or not at all. Much of the failure is attributed to the relatively low solubility of these compounds in lipid. Inclusion of a term in octanol solubility (in place of lipid solubility, which is generally unavailable) considerably improves the quality of the relationship (r = 0.95). It is speculated that the octanol solubility term compensates for the relatively low solubility of large compounds in lipid.

OSTI ID:
5477424
Journal Information:
Environmental Science and Technology; (USA), Vol. 25:3; ISSN 0013-936X
Country of Publication:
United States
Language:
English