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Title: Reduction of the nocturnal rise in pineal melatonin levels in rats exposed to 60-Hz electric fields in utero and for 23 days after birth

Rats exposed to 60-Hz electric fields of either 10, 65, or 130 kV/m from conception to 23 days of age exhibited reduced peak nighttime pineal melatonin contents compared to unexposed controls. As a group, the exposed rats also exhibited a phase delay, estimated at approximately 1.4 hours, in the occurrence of the nocturnal melatonin peak. No clear dose-response relationship was noticed over the range of electric field strengths used as treatments in these experiments. These are the first studies concerned with the effects of electric field exposure on the pineal melatonin rhythm in immature rats and the findings are generally consistent with those obtained using adult rats, where electric field exposure has been shown to abolish the nighttime rhythm in pineal melatonin concentrations. 15 refs., 1 fig., 1 tab.
Authors:
; ; ;
Publication Date:
OSTI Identifier:
5477265
Report Number(s):
PNL-SA-15028; CONF-8709165-2
ON: DE88005684
DOE Contract Number:
AC06-76RL01830
Resource Type:
Conference
Resource Relation:
Conference: International workshop on the pineal gland and cancer, Tubingen, F.R. Germany, 8 Sep 1987; Other Information: Paper copy only, copy does not permit microfiche production
Research Org:
Pacific Northwest Lab., Richland, WA (USA); Texas Univ., San Antonio (USA). Health Science Center
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ELECTRIC FIELDS; BIOLOGICAL EFFECTS; MELATONIN; NOCTURNAL VARIATIONS; DOSE-RESPONSE RELATIONSHIPS; EMBRYOS; JUVENILES; PINEAL GLAND; PRENATAL EXPOSURE; RATS; AMINES; ANIMALS; AROMATICS; AZAARENES; AZOLES; BODY; GLANDS; HETEROCYCLIC COMPOUNDS; INDOLES; MAMMALS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PYRROLES; RODENTS; TRYPTAMINES; VARIATIONS; VERTEBRATES 560400* -- Other Environmental Pollutant Effects