Diagnostic value of exercise testing in asbestosis
- Institute of Occupational Medicine in the Mining and Metallurgical Industry, Sosnowiec (Poland)
The diagnostic value of simple exercise testing was examined in 81 current male asbestos-cement workers, divided into four groups according to the International Labour Office (ILO) category of irregular opacities: 0/0, 25; 1/1, 24; 1/2, 22; and 2/2, 10 men. An increasing X-ray score was accompanied by more severe functional abnormality in keeping with the development of a restrictive defect. Symptom-limited oxygen uptake (VO2SL) did not depend on the X-ray grade and was 76.7, 71.9, 68.7, and 73.5% pv, respectively, for the four groups. Subjects with ILO score 1/1 had significantly higher exercise ventilation at O2 uptake of 1.01.min-1 (VE 1.0) than those with grade 0/0. End-exercise tidal volume (VTSL in 1) decreased with an increasing X-ray score: 2.14, 1.98, 1.85, and 1.62, respectively. VTSL standardized for vital capacity (VTSL/VC) followed the same pattern. Asbestosis was diagnosed in 25 men, in whom VE 1.0 was significantly higher (p less than .02) and VTSL lower (p less than .01) than in the 0/0 group. VO2SL was similar in both groups. The findings suggest that VE 1.0 and VTSL may be early functional indicators of asbestos-related interstitial lung fibrosis. The measurement of both exercise indices may increase the certainty of clinical diagnosis of asbestosis in subjects with less advanced disease.
- OSTI ID:
- 5465339
- Journal Information:
- American Journal of Industrial Medicine; (USA), Vol. 16:3; ISSN 0271-3586
- Country of Publication:
- United States
- Language:
- English
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ASBESTOS
TOXICITY
LUNGS
FIBROSIS
RESPIRATORY SYSTEM DISEASES
DIAGNOSIS
BIOMEDICAL RADIOGRAPHY
EXERCISE
MAN
OCCUPATIONAL EXPOSURE
PERSONNEL
X RADIATION
ANIMALS
BODY
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTROMAGNETIC RADIATION
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MAMMALS
MEDICINE
NUCLEAR MEDICINE
ORGANS
PATHOLOGICAL CHANGES
PRIMATES
RADIATIONS
RADIOLOGY
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560300* - Chemicals Metabolism & Toxicology
550602 - Medicine- External Radiation in Diagnostics- (1980-)