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Title: Oral verrucous carcinoma. Treatment with radiotherapy

Fifty-two cases of oral verrucous carcinoma treated with radiotherapy at the Regional Cancer Centre, Trivandrum, Kerala, India in 1982 were evaluated to determine the distribution within the oral cavity, clinical extent, and effectiveness of radiotherapy in controlling the disease. The most common site was the buccal mucosa. Fifty percent of the patients had clinically negative regional lymph nodes and 33% were in earlier stages (T1, T2, N0, and M0). The overall 3-year no evidence of disease (NED) survival rate was 44%. The 3-year NED survival rate with radium implant was 86%. We cannot comment on anaplastic transformation after radiotherapy because our treatment failures have not been subjected for biopsy concerning this matter. Because the results are comparable with those of well-differentiated squamous cell carcinoma, we think that the treatment policies advocated for oral squamous cell carcinoma are also applicable to oral verrucous carcinoma.
Authors:
; ; ;
Publication Date:
OSTI Identifier:
5442524
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cancer (Philadelphia); (United States); Journal Volume: 61:3
Research Org:
Medical College Campus, Trivandrum, Kerala (India)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CARCINOMAS; RADIOTHERAPY; ORAL CAVITY; DOSE-RESPONSE RELATIONSHIPS; INDIA; PATIENTS; RADIATION SOURCE IMPLANTS; RADIUM; SURVIVAL CURVES; ALKALINE EARTH METALS; ASIA; DEVELOPING COUNTRIES; DIGESTIVE SYSTEM; DISEASES; ELEMENTS; IMPLANTS; MEDICINE; METALS; NEOPLASMS; NUCLEAR MEDICINE; RADIATION SOURCES; RADIOLOGY; THERAPY 550604* -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)