Radiologic findings in late-onset systemic lupus erythematosus
Systemic lupus erythematosus in the elderly has a different clinical and serologic course from that in young patients. Radiographic findings in patients in whom the diagnosis was made after age 50 were compared with findings in younger patients to see if the radiologic patterns are also different. The only significant radiographic difference between the two groups was that the older group had a greater incidence of soft-tissue swelling of the hands and wrists (p < 0.001). There was no significant difference in osteopenia, erosion, soft-tissue calcification, alignment abnormalities, or intrathoracic findings. Of 24 patients over age 50, two developed lymphoma and another developed multiple myeloma. The data agree with clinical observations that there is a higher incidence of arthritis in late-onset lupus, but clinical findings of increased incidence of pleuropericardial disease are not confirmed radiographically. The coincidence of hematologic malignancy with late-onset lupus in this series is noteworthy.
- Research Organization:
- Harvard Medical School, Boston, MA
- OSTI ID:
- 5441164
- Journal Information:
- AJR, Am. J. Roentgenol.; (United States), Vol. 140:3
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
LUPUS
CORRELATIONS
PATHOLOGY
NEOPLASMS
SKELETON
BIOMEDICAL RADIOGRAPHY
ADULTS
BONE JOINTS
CHEST
ELDERLY PEOPLE
HEMIC DISEASES
PATIENTS
AGE GROUPS
BACTERIAL DISEASES
BODY
BODY AREAS
DIAGNOSTIC TECHNIQUES
DISEASES
HUMAN POPULATIONS
INFECTIOUS DISEASES
MEDICINE
MINORITY GROUPS
NUCLEAR MEDICINE
ORGANS
POPULATIONS
RADIOLOGY
SKIN DISEASES
TUBERCULOSIS
550602* - Medicine- External Radiation in Diagnostics- (1980-)
550900 - Pathology