Distributions of /sup 35/S-sulfate and /sup 3/H-glucosamine in the angular region of the hamster: light and electron microscopic autoradiography
The distribution of /sup 35/S-sulfate and /sup 3/H-glucosamine in the angular region of the hamster was studied by light and electron microscopic autoradiography following intraperitoneal injection of these compounds to hamsters. Exposed silver grains of /sup 35/S-sulfate were concentrated in the trabecular meshwork, sclera, and cornea, and grains of /sup 3/H-glucosamine were localized in the trabecular region. The radioactivity of both isotopes was observed in the Golgi apparatuses of the endothelial cells of the angular aqueous plexus and the trabecular meshwork. The grains were noted over the entire cytoplasm, except for the nucleus, and then were incorporated into the amorphous substance and collagen fibers in the region adjacent to the angular aqueous sinus. These results suggest that endothelial cells in the angular region synthesize and secrete the sulfated glycosaminoglycans and hyaluronic acid.
- Research Organization:
- Department of Ophthalmology, Faculty of Medicine, Kyushu University, Fukuoka, Japan
- OSTI ID:
- 5433281
- Journal Information:
- Invest. Ophthalmol. Visual Sci.; (United States), Vol. 24:6
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
GLUCOSAMINE
TISSUE DISTRIBUTION
SULFATES
AUTORADIOGRAPHY
HAMSTERS
LABELLED COMPOUNDS
SULFUR 35
TRITIUM
AMINES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CARBOHYDRATES
DAYS LIVING RADIOISOTOPES
DISTRIBUTION
EVEN-ODD NUCLEI
HEXOSAMINES
HEXOSES
HYDROGEN ISOTOPES
ISOTOPES
LIGHT NUCLEI
MAMMALS
MONOSACCHARIDES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
OXYGEN COMPOUNDS
RADIOISOTOPES
RODENTS
SACCHARIDES
SULFUR COMPOUNDS
SULFUR ISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
550501* - Metabolism- Tracer Techniques