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Title: Mus spretus LINE-1s in the Mus musculus domesticus inbred strain C57BL/6J are from two different Mus spretus LINE-1 subfamilies

Journal Article · · Genetics
OSTI ID:543051
; ;  [1]
  1. Univ. of Texas Health Science Center, San Antonio, TX (United States)

A LINE-1 element, L1C105, was found in the Mus musculus domesticus inbred strain, C57BL/6J. Upon sequencing, this element was found to belong to a M. spretus LINE-1 subfamily originating within the last 0.2 million years. This is the second spretus-specific LINE-1 subfamily found to be represented in C57BL/6J. Although it is unclear how these M. spretus LINE-1s transferred from M. spretus to M. m. domesticus, it is now clear that at least two different spretus LINE-1 sequences have recently transferred. The limited divergence between the C57BL/6J spretus-like LINE-1s and their closest spretus ancestors suggests that the transfer did not involve an exceptionally long lineage of sequential transpositions. 54 refs., 6 figs.

OSTI ID:
543051
Journal Information:
Genetics, Vol. 142, Issue 2; Other Information: PBD: Feb 1996
Country of Publication:
United States
Language:
English