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Title: Nuclear resonance scattering measurement of human iron stores

Journal Article · · Med. Phys.; (United States)
DOI:https://doi.org/10.1118/1.595751· OSTI ID:5410976

Hepatic iron stores were measured noninvasively in 31 patients (thalassemia, hemodialysis, hemosiderosis, refractory anemia) with suspected iron overload, employing a nuclear resonance scattering (NRS) technique. The thalassemia patients were undergoing desferrioxamine chelation therapy during the NRS measurements. The hemodialysis patients were measured before chelation therapy. Iron levels measured by NRS were in general agreement with those determined in liver biopsies by atomic absorption spectroscopy. In addition, NRS measurements from the thorax of some of these patients suggest that this method may also prove useful for clinical assessment of cardiac iron.

Research Organization:
Brookhaven National Laboratory, Medical Research Center, Upton, New York 11973
DOE Contract Number:
AC02-76CH00016
OSTI ID:
5410976
Journal Information:
Med. Phys.; (United States), Vol. 12:4
Country of Publication:
United States
Language:
English