Measurement of the plasma clearance of urographic contrast media for the determination of glomerular filtration rate
Further experience with a new method to determine glomerular filtration rate is presented. The method depends on measurement by an x-ray fluorescence technique of the plasma disappearance of the injected iodine in standard nonionic radiographic contrast media used during excretory urography. The results of comparison of contrast clearance with /sup 99m/technetium-diethylenetriaminepentaacetic acid clearance in 33 cases showed excellent agreement with a correlation coefficient of 0.95. Reproducibility of the contrast clearance method was confirmed by repeated examination of 10 plasma samples at weekly intervals for 6 weeks, the results of which showed no significant differences. The contrast clearance technique for the measurement of glomerular filtration rate during excretory urography is simple, quick and accurate, and merits further development.
- Research Organization:
- Stepping Hill Hospital, Stockport, Manchester, England
- OSTI ID:
- 5410853
- Journal Information:
- J. Urol.; (United States), Vol. 139:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
DTPA
BLOOD-PLASMA CLEARANCE
KIDNEYS
BIOMEDICAL RADIOGRAPHY
DYNAMIC FUNCTION STUDIES
CONTRAST MEDIA
IOHEXOL
ISOMERIC NUCLEI
ORGANOMETALLIC COMPOUNDS
TECHNETIUM 99
X-RAY FLUORESCENCE ANALYSIS
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACIDS
CHELATING AGENTS
CHEMICAL ANALYSIS
CLEARANCE
DIAGNOSTIC TECHNIQUES
DRUGS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NONDESTRUCTIVE ANALYSIS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
RADIOISOTOPES
RADIOLOGY
RADIOPROTECTIVE SUBSTANCES
TECHNETIUM ISOTOPES
X-RAY EMISSION ANALYSIS
YEARS LIVING RADIOISOTOPES
550602* - Medicine- External Radiation in Diagnostics- (1980-)