Maximal aerobic capacity at several ambient concentrations of carbon monoxide at several altitudes. Research report, April 1984-January 1988
To assess the combined effects of altitude and acute carbon monoxide exposure, 11 male and 12 female subjects, all nonsmokers in good health, were given incremental maximal aerobic-capacity tests. Each subject, after attaining the required altitude and ambient carbon monoxide level, performed the maximal aerobic capacity test. Blood samples were drawn at several points in the aerobic capacity test protocol, and analyzed for hemoglobin, hematocrit, plasma proteins, lactates, and carboxyhemoglobin. Carbon-monoxide-carboxyhemoglobin uptake rates were derived from the submaximal workloads. Despite increases in carboxyhemoglobin, no additional significant decreases in maximal aerobic capacity were observed. Immediately prior to and at maximal workloads, carbon monoxide shifted into extravascular spaces and returned to the vascular space within five minutes after exercise stopped.
- Research Organization:
- California Univ., Santa Barbara, CA (USA). Environmental Stress Inst.
- OSTI ID:
- 5410214
- Report Number(s):
- PB-89-217723/XAB
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALTITUDE
BIOLOGICAL EFFECTS
CARBON MONOXIDE
AEROBIC CONDITIONS
AIR POLLUTION
ANOXIA
CARBOXYHEMOGLOBIN
DOSE-RESPONSE RELATIONSHIPS
ENVIRONMENTAL EXPOSURE
HEMOGLOBIN
OXYGEN
PROGRESS REPORT
CARBON COMPOUNDS
CARBON OXIDES
CARBOXYLIC ACIDS
CHALCOGENIDES
DOCUMENT TYPES
ELEMENTS
GLOBINS
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
NONMETALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PIGMENTS
POLLUTION
PORPHYRINS
PROTEINS
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560300 - Chemicals Metabolism & Toxicology