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Title: Thyroid uptake and imaging with iodine-123 at 4-5 hours: replacement of the 24-hour iodine-131 standard

A study was carried out to determine the suitability of utilizing a 4 to 5 hr interval from administration of Iodine-123 to imaging and uptake measurement as a replacement for the 24-hr standard originally established with Iodine-131. In 55 patients who underwent scintigraphy at 4 and 24 hr, there was no discrepancy between paired images. In 55 patients who had uptake measured at 4 and 24 hr and in 191 patients who had uptake measured at 5 and 24 hr, the early measurements proved equal or better discriminants of euthyroid from hyperthyroid patients. In our institutions, these findings and the logistical advantages of completing the exam in 4-5 hr led us to abandon the 24-hr study in the majority of patients.
Authors:
; ; ; ;
Publication Date:
OSTI Identifier:
5400755
Resource Type:
Journal Article
Resource Relation:
Journal Name: J. Nucl. Med.; (United States); Journal Volume: 26:8
Research Org:
David Grant USAF Medical Center, Travis AFB, CA
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ENDOCRINE DISEASES; DIAGNOSIS; IODINE 123; UPTAKE; THYROID; SCINTISCANNING; CALIBRATION STANDARDS; HYPOTHYROIDISM; IODINE 131; PATIENTS; THYROIDITIS; TIME DEPENDENCE; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; ENDOCRINE GLANDS; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; STANDARDS 550601* -- Medicine-- Unsealed Radionuclides in Diagnostics