Damaging effects of visible light. Progress report

Technical Report · Mon Feb 01 00:00:00 EST 1982

OSTI ID:5386509

Williams, T P; Baker, B N

The right eyes of anesthetized, ten week old albino rats are exposed to constant photon fluxes at 6 wavelengths for 6 hours. The left eye of each animal is patched during the exposure and is used as control. Histologic examination of retinal sections disclosed a region in the superior retina which is more damaged than are other areas. Attempting to ascertain an action spectrum by measuring ONL lost in this sensative region fails. However, it is shown that, when ONL thickness is integrated over the entire retinal sections, a rhodopsin action-spectrum emerges. It is concluded that (i) retinal light damage in the albino rat under these conditions is rhodopsin mediated; and (ii) assessment of the extent of damage is best made by some method which integrates over the entire retinal section. The latter methodology is not routinely incorporated into studies of retinal light-damage but probably should be.

• Research Organization: Florida State Univ., Tallahassee (USA)
• DOE Contract Number: AS05-78OR06021
• OSTI ID: 5386509
• Report Number(s): DOE/OR/06021-4; ON: DE82011597
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
RETINA
PATHOLOGICAL CHANGES
VISIBLE RADIATION
BIOLOGICAL EFFECTS
EYES
HISTOLOGICAL TECHNIQUES
PIGMENTS
RATS
ANIMALS
BODY
BODY AREAS
ELECTROMAGNETIC RADIATION
FACE
HEAD
MAMMALS
ORGANS
RADIATIONS
RODENTS
SENSE ORGANS
VERTEBRATES
560400* - Other Environmental Pollutant Effects
551000 - Physiological Systems