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Title: Bronchial artery infusion of mitomycin C in carcinoma of the lung

Fifteen patients with bronchial carcinoma were treated with infusions of 10 mg Mitomycin C (MMC) in the bronchial artery feeding the tumor. The treatment was repeated three times with 2-3 weeks interval between treatments. Half of the patients then received radiation to the tumor area and mediastinum. All tumors decreased in size, complete remission occurred in two and partial remission in five patients. Survival time, however, was not prolonged and esophageal complications occurred in several patients.
Authors:
; ;
Publication Date:
OSTI Identifier:
5350390
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovasc. Interv. Radiol.; (United States); Journal Volume: 6:2
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ARTERIES; BIOMEDICAL RADIOGRAPHY; BRONCHI; CARCINOMAS; CHEMOTHERAPY; RADIOTHERAPY; CONTRAST MEDIA; IMAGES; INFUSION; INJECTION; LUNGS; MITOMYCIN; PATIENTS; SIDE EFFECTS; SURVIVAL TIME; ANTI-INFECTIVE AGENTS; ANTIBIOTICS; ANTIMITOTIC DRUGS; ANTINEOPLASTIC DRUGS; BLOOD VESSELS; BODY; CARDIOVASCULAR SYSTEM; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; INTAKE; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY 550602* -- Medicine-- External Radiation in Diagnostics-- (1980-); 550600 -- Medicine; 550603 -- Medicine-- External Radiation in Therapy-- (1980-)