Indications for and limitations of bone scintigraphy in osteogenic sarcoma: a review of 55 patients

Journal Article · Tue Sep 01 00:00:00 EDT 1981 · Cancer (Philadelphia); (United States)

DOI:https://doi.org/10.1002/1097-0142(19810901)48:5<1133::AID-CNCR2820480515>3.0.CO;2-H· OSTI ID:5309867

McKillop, J H; Etcubanas, E; Goris, M L

The value of radioisotope bone scanning at the time of presentation and serially during follow-up has been evaluated in 55 patients with biopsy-proven osteogenic sarcoma. Many of the patients studied were treated with adjuvant chemotherapy. Bone metastases were detected at presentation in only one patient and in a second patient, proximal extension of the primary tumor not evident on radiographs was demonstrated by the radioisotope technique. During fellow-up, 20 patients experienced bone metastases and each had an abnormal bone scan. Eleven of these patients were asymptomatic for bone metastases at the time the scan became abnormal. Seven patients experienced bone metastases as their first site of tumor recurrence. The detection rate for soft tissue metastases was low, but the scan indicated stump recurrence in three patients. Although the yield is small, bone scanning is justified at presentation be cause the results may profoundly after the management. During follow-up, routine bone cans are indicated in all patients, whether they have symptoms or not.

• OSTI ID: 5309867
• Journal Information: Cancer (Philadelphia); (United States), Vol. 48:5
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
BONE SEEKERS
DIAGNOSTIC USES
METASTASES
DIAGNOSIS
OSTEOSARCOMAS
SKELETON
SCINTISCANNING
PATHOLOGY
PATIENTS
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
ISOTOPES
NEOPLASMS
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SARCOMAS
SKELETAL DISEASES
USES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550901 - Pathology- Tracer Techniques