Method for labelling leucocytes with indium In-111 oxine

Patent · Tue Mar 03 00:00:00 EST 1992

OSTI ID:5272947

Kaminsky, D

This patent describes an improved method for radio-labelling leucocytes with Indium In-111 oxine. It comprises separating the leucocytes from whole blood for obtaining separated leucocytes mixed with residual red blood cells; and then labelling the separated leucocytes with Indium In-111 oxine; wherein the improvement comprises the following further step: depleting residual red blood cells from the separated leucocytes by resuspending the leucocytes in an isotonic saline solution, then rocking the resuspended leucocytes for causing the leucocytes to preferentially settle out, and then removing residual red blood cells which remain suspended within the supernatant isotonic saline solution.

• Assignee: Syncor International Corp., Chatsworth, CA (United States)
• Patent Number(s): US 5093104; A
• Application Number: PPN: US 7-395353
• OSTI ID: 5272947
• Resource Relation: Patent File Date: 17 Aug 1989
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
59 BASIC BIOLOGICAL SCIENCES
INDIUM 111
DIAGNOSTIC USES
LEUKOCYTES
LABELLING
OXINE
AROMATICS
AZAARENES
AZINES
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PYRIDINES
QUINOLINES
RADIOISOTOPES
USES
400703* - Radiochemistry & Nuclear Chemistry- Radioisotope Production
550901 - Pathology- Tracer Techniques
551001 - Physiological Systems- Tracer Techniques