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Title: Influence of field size, treatment modality, commissure involvement and histology in the treatment of early vocal cord cancer with irradiation

Abstract

One hundred and thirty-seven patients with TNM staged T1 glottic cancer were treated from 1966 to 1980. Patients were treated either with /sup 60/Co teletherapy units or 4 MeV linear accelerators with different daily and weekly fractionation schemes. A recurrent-free survival was attained in 80% of the patients 2 years after primary treatment with radiation therapy. There were 27 local recurrences of which 82% were salvaged with surgery for an overall adjusted survival of 95%. Poorly differentiated tumors and those involving the anterior commissure were more likely to develop a local recurrence. Voice quality remained good to excellent in 79% of patients. Edema and mucositis were the major side effects.

Authors:
; ; ; ;
Publication Date:
Research Org.:
St. Mary's Hospital and Medical Center, San Francisco, CA
OSTI Identifier:
5269307
Resource Type:
Journal Article
Journal Name:
Int. J. Radiat. Oncol., Biol. Phys.; (United States)
Additional Journal Information:
Journal Volume: 11:7
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; CARCINOMAS; RADIOTHERAPY; EDEMA; RADIOINDUCTION; LARYNX; SIDE EFFECTS; COBALT 60; GAMMA RADIATION; HISTOLOGY; LINEAR ACCELERATORS; MEV RANGE 01-10; MUCOUS MEMBRANES; PAIN; ACCELERATORS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; COBALT ISOTOPES; DISEASES; ELECTROMAGNETIC RADIATION; ENERGY RANGE; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; MEMBRANES; MEV RANGE; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; PATHOLOGICAL CHANGES; RADIATIONS; RADIOISOTOPES; RADIOLOGY; RESPIRATORY SYSTEM; SYMPTOMS; THERAPY; YEARS LIVING RADIOISOTOPES; 550603* - Medicine- External Radiation in Therapy- (1980-); 560151 - Radiation Effects on Animals- Man

Citation Formats

Olszewski, S J, Vaeth, J M, Green, J P, Schroeder, A F, and Chauser, B. Influence of field size, treatment modality, commissure involvement and histology in the treatment of early vocal cord cancer with irradiation. United States: N. p., 1985. Web. doi:10.1016/0360-3016(85)90249-4.
Olszewski, S J, Vaeth, J M, Green, J P, Schroeder, A F, & Chauser, B. Influence of field size, treatment modality, commissure involvement and histology in the treatment of early vocal cord cancer with irradiation. United States. https://doi.org/10.1016/0360-3016(85)90249-4
Olszewski, S J, Vaeth, J M, Green, J P, Schroeder, A F, and Chauser, B. 1985. "Influence of field size, treatment modality, commissure involvement and histology in the treatment of early vocal cord cancer with irradiation". United States. https://doi.org/10.1016/0360-3016(85)90249-4.
@article{osti_5269307,
title = {Influence of field size, treatment modality, commissure involvement and histology in the treatment of early vocal cord cancer with irradiation},
author = {Olszewski, S J and Vaeth, J M and Green, J P and Schroeder, A F and Chauser, B},
abstractNote = {One hundred and thirty-seven patients with TNM staged T1 glottic cancer were treated from 1966 to 1980. Patients were treated either with /sup 60/Co teletherapy units or 4 MeV linear accelerators with different daily and weekly fractionation schemes. A recurrent-free survival was attained in 80% of the patients 2 years after primary treatment with radiation therapy. There were 27 local recurrences of which 82% were salvaged with surgery for an overall adjusted survival of 95%. Poorly differentiated tumors and those involving the anterior commissure were more likely to develop a local recurrence. Voice quality remained good to excellent in 79% of patients. Edema and mucositis were the major side effects.},
doi = {10.1016/0360-3016(85)90249-4},
url = {https://www.osti.gov/biblio/5269307}, journal = {Int. J. Radiat. Oncol., Biol. Phys.; (United States)},
number = ,
volume = 11:7,
place = {United States},
year = {Mon Jul 01 00:00:00 EDT 1985},
month = {Mon Jul 01 00:00:00 EDT 1985}
}