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Title: Spurious thyroid cancer metastasis: saliva contamination artifact in high dose iodine-131 metastases survey

The use of high dose /sup 131/I for workup of thyroid cancer patients increases the chance of contamination artifact which may mimic metastases. Two elderly male patients with follicular carcinoma of the thyroid had salivary contamination artifacts on metastatic survey scans. These patients received a 1 and 10 mCi dose of /sup 131/I, respectively. The artifacts were recognized only retrospectively when follow-up scans were obtained and compared. The characteristics of contamination artifacts and several methods to confirm these are discussed.
Authors:
; ; ;
Publication Date:
OSTI Identifier:
5232519
Resource Type:
Journal Article
Resource Relation:
Journal Name: J. Nucl. Med.; (United States); Journal Volume: 5
Research Org:
Indiana Univ. School of Medicine, Indianapolis
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; RADIOPHARMACEUTICALS; IMPURITIES; THYROID; RADIOISOTOPE SCANNING; CARCINOMAS; ERRORS; IODINE 131; METASTASES; PATIENTS; SALIVA; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BODY; BODY FLUIDS; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DISEASES; DRUGS; ENDOCRINE GLANDS; GLANDS; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPES 550601* -- Medicine-- Unsealed Radionuclides in Diagnostics