Indium-111 leukocyte imaging in patients with rheumatoid arthritis

Journal Article · Sat Mar 01 00:00:00 EST 1986 · J. Nucl. Med.; (United States)

OSTI ID:5232435

Uno, K; Matsui, N; Nohira, K; Suguro, T; Kitakata, Y; Uchiyama, G; Miyoshi, T; Uematsu, S; Inoue, S; Arimizu, N

This study evaluates the usefulness of labeled leukocyte imaging in patients with rheumatoid arthritis. In 33 patients, the incidence of pain and swelling in 66 wrist joints and 66 knee joints was compared with the accumulation of (/sup 111/In)leukocytes. No accumulation of (/sup 111/In)leukocytes was seen in any of the patients' wrists (0/12) or knee joints (0/14) when both pain and swelling were absent. In contrast, 93% (25/27) of wrist joints and 80% (24/30) of knee joints with both pain and swelling were positive by (/sup 111/In)leukocyte scintigraphy. There was little correlation between the stage of the disease, as determined by radiography, and (/sup 111/In)leukocyte accumulation. This study suggests that (/sup 111/In)leukocyte imaging may be a reliable procedure for monitoring the activity of rheumatoid arthritis, especially for confirming the lack of an ongoing inflammatory response.

• Research Organization: Chiba Univ. School of Medicine, Japan
• OSTI ID: 5232435
• Journal Information: J. Nucl. Med.; (United States), Vol. 3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BONE JOINTS
SCINTISCANNING
DIAGNOSIS
INDIUM 111
INFLAMMATION
LEUKOCYTES
PAIN
PATIENTS
RHEUMATIC DISEASES
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SKELETAL DISEASES
SKELETON
SYMPTOMS
550601* - Medicine- Unsealed Radionuclides in Diagnostics