Effects of flavonoids on human lymphocyte proliferative responses
Journal Article
·
· Prog. Clin. Biol. Res.; (United States)
OSTI ID:5230278
Flavonoids reversibly inhibit lymphocyte proliferative responses to phytomitogens, soluble antigens and phorbol esters by blocking an early event or events that follow stimulation. Quercetin and tangeretin inhibit thymidine transport in stimulated lymphocytes. These flavonoids reversibly inhibit antigen processing by monocytes and inhibit the expression of class II histocompatibility (DR) antigens in PBM cells.
- Research Organization:
- Veterans Administration Medical Center, Buffalo, NY
- OSTI ID:
- 5230278
- Journal Information:
- Prog. Clin. Biol. Res.; (United States), Journal Name: Prog. Clin. Biol. Res.; (United States)
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
FLAVONES
BIOLOGICAL EFFECTS
LYMPHOCYTES
CELL PROLIFERATION
DNA
INHIBITION
PHORBOL ESTERS
QUERCETIN
THYMIDINE
TRITIUM COMPOUNDS
ANIMAL CELLS
AROMATICS
AZINES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARCINOGENS
CONNECTIVE TISSUE CELLS
ESTERS
FLAVENOIDS
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
LABELLED COMPOUNDS
LEUKOCYTES
MATERIALS
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PHENOLS
POLYPHENOLS
PYRANS
PYRIMIDINES
RIBOSIDES
SOMATIC CELLS
560301* - Chemicals Metabolism & Toxicology- Cells- (-1987)
FLAVONES
BIOLOGICAL EFFECTS
LYMPHOCYTES
CELL PROLIFERATION
DNA
INHIBITION
PHORBOL ESTERS
QUERCETIN
THYMIDINE
TRITIUM COMPOUNDS
ANIMAL CELLS
AROMATICS
AZINES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARCINOGENS
CONNECTIVE TISSUE CELLS
ESTERS
FLAVENOIDS
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
LABELLED COMPOUNDS
LEUKOCYTES
MATERIALS
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PHENOLS
POLYPHENOLS
PYRANS
PYRIMIDINES
RIBOSIDES
SOMATIC CELLS
560301* - Chemicals Metabolism & Toxicology- Cells- (-1987)