Bone and bone-marrow blood flow in chronic granulocytic leukemia and primary myelofibrosis

Journal Article · Mon Mar 01 00:00:00 EST 1982 · J. Nucl. Med.; (United States)

OSTI ID:5211071

Lahtinen, R; Lahtinen, T; Romppanen, T

Blood flow in hematopoietic bone marrow and in nonhematopoietic bone has been measured with a Xe-133 washout method in 20 patients with chronic granulocytic leukemia (CGL) and in seven with primary myelofibrosis. Age-matched healthy persons served as controls. Bone-marrow blood flow in CGL was dependent upon the phase of the disease. In the metamorphosis phase, bone-marrow blood flow was high compared with that in the well-controlled phase. Apart from the initial phase, the mean values for bone blood flow in CGL were increased compared with the values of the healthy controls. In myelofibrosis the bone blood flow was also increased. Bone-marrow blood flow in these diseases was dependent upon the cellularity of bone marrow as measured morphometrically.

• Research Organization: Kuopio University Central Hospital, Finland
• OSTI ID: 5211071
• Journal Information: J. Nucl. Med.; (United States), Vol. 23:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD FLOW
RADIOISOTOPE SCANNING
FIBROSIS
PATHOLOGY
LEUKEMIA
XENON 133
BONE MARROW
PATIENTS
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DISEASES
EVEN-ODD NUCLEI
HEMATOPOIETIC SYSTEM
HEMIC DISEASES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NEOPLASMS
NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIOISOTOPES
TISSUES
XENON ISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics