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Title: Benzalkonium chloride. Health hazard evaluation report

Health hazards associated with the use of benzalkonium chlorides (BAC) are reviewed. Benzalkonium chloride is extensively used as a cationic disinfectant. It is found in a great many over-the-counter and prescription eye products, disinfectants, shampoos, and deodorants, and is used in concentrations that range from 0.001 to 0.01% in eyedrops, up to 2.5% in concentrated liquid disinfectants. Solutions of 0.03 to 0.04% BAC may cause temporary eye irritation in humans but are unlikely to cause any skin response except in persons allergic to quaternary ammonium compounds. Inhalation of a vaporized 10% solution of BAC produced a bronchospasmodic reaction in a previously sensitized individual. At present no other human health effects from BAC have been documented or inferred from exposure to such dilute concentrations.
Authors:
Publication Date:
OSTI Identifier:
5210900
Report Number(s):
BNL-34209
ON: DE84008058
DOE Contract Number:
AC02-76CH00016
Resource Type:
Technical Report
Research Org:
Brookhaven National Lab., Upton, NY (USA)
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; DETERGENTS; BIOLOGICAL EFFECTS; HEALTH HAZARDS; QUATERNARY COMPOUNDS; DISINFECTANTS; FUNGICIDES; PERSONNEL; WORKING CONDITIONS; ADDITIVES; AMINES; AMMONIUM COMPOUNDS; EMULSIFIERS; GERMICIDES; HAZARDS; ORGANIC COMPOUNDS; PESTICIDES; SURFACTANTS; WETTING AGENTS 560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987); 560305 -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)