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Title: UV action spectra for mammalian systems: their implications for the predicted effects of ozone depletion on skin cancer incidence

The predicted environmental effect of UV-B depend on the action spectrum for the response studied. Since such spectra change rapidly - usually decreasing with increasing wavelength - and since the biological effects depend on the product of the action spectrum and the sun's spectrum at the surface of the earth which decreases with decreasing wavelength, a slight change in action spectrum will markedly influence the predicted effects of ozone depletion on biological systems. Thus, the key, but by no means only step in the prediction, is a knowledge of the action spectrum. Unfortunately, it is rare that we know or even hope to know the spectrum for biological systems of interest such as skin cancer induction, nor is it possible to do experiments with solar simulators on many systems. Hence, we must base our predictions on the photobiological properties of simple systems and the knowledge of their action spectra and general biological theories connecting simple cells with higher organisms.
Authors:
Publication Date:
OSTI Identifier:
5173973
Report Number(s):
BNL-31178; CONF-820537-1
ON: DE82009612; TRN: 82-014129
DOE Contract Number:
AC02-76CH00016
Resource Type:
Conference
Resource Relation:
Conference: Conference on biological effects of UV-B radiation, Munich, F.R. Germany, 25 May 1982; Other Information: Portions of document are illegible
Research Org:
Brookhaven National Lab., Upton, NY (USA)
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; NEAR ULTRAVIOLET RADIATION; CARCINOGENESIS; BIOLOGICAL RADIATION EFFECTS; DNA; FREQUENCY DEPENDENCE; IMMUNE REACTIONS; MAN; OZONE; SKIN; SOLAR RADIATION; ULTRAVIOLET SPECTRA; ANIMALS; BIOLOGICAL EFFECTS; BODY; ELECTROMAGNETIC RADIATION; MAMMALS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANS; PATHOGENESIS; PRIMATES; RADIATION EFFECTS; RADIATIONS; SPECTRA; STELLAR RADIATION; ULTRAVIOLET RADIATION; VERTEBRATES 560151* -- Radiation Effects on Animals-- Man; 560114 -- Radiation Effects on Biochemicals-- In Animals-- (-1987)