Detection of chrysotile asbestos in workers urine
Abstract
Urinary asbestos concentrations were evaluated as an indicator of occupational exposure to chrysotile asbestos via inhalation and ingestion. Detection of asbestos in the urine represents the first step in developing a biological indicator of exposure. Such an indicator could be used to supplement exposure data from workplace air sampling. A biological indicator would be particularly valuable in evaluating workers with intermittent airborne asbestos exposures and in determining if airborne exposure results in penetration of asbestos through the lung or gastro-intestinal tract. Transmission electron microscopy was selected as the most sensitive technique for identification of all sizes of asbestos fibers which might appear in the urine. The levels of chrysotile asbestos detected in the urine of five workers were significantly greater than the asbestos concentrations in matched field blanks. Also, the workers urinary asbestos levels were significantly greater than the concentrations found in the control group. Finally, the levels of chrysotile asbestos detected in the urine of two of six controls were significantly greater than those in matched field blanks. Although the project was not specifically designed to correlate urinary and airborne asbestos concentrations, preliminary data indicated that a correlation did not exist between these factors.
- Authors:
- Publication Date:
- Research Org.:
- Standard Oil Co., Indiana, Chicago, IL
- OSTI Identifier:
- 5147377
- Resource Type:
- Journal Article
- Journal Name:
- Am. Ind. Hyg. Assoc. J.; (United States)
- Additional Journal Information:
- Journal Volume: 3
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ASBESTOS; BIOLOGICAL INDICATORS; OCCUPATIONAL EXPOSURE; TRANSMISSION ELECTRON MICROSCOPY; URINE; CHEMICAL ANALYSIS; CHICAGO; GASTROINTESTINAL TRACT; INGESTION; INHALATION; LUNGS; OCCUPATIONS; PERSONNEL; BIOLOGICAL MATERIALS; BIOLOGICAL WASTES; BODY; BODY FLUIDS; DIGESTIVE SYSTEM; ELECTRON MICROSCOPY; FEDERAL REGION V; ILLINOIS; INTAKE; MATERIALS; MICROSCOPY; NORTH AMERICA; ORGANS; RESPIRATORY SYSTEM; USA; WASTES; 560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
Citation Formats
Finn, M B, and Hallenbeck, W H. Detection of chrysotile asbestos in workers urine. United States: N. p., 1985.
Web. doi:10.1080/15298668591394581.
Finn, M B, & Hallenbeck, W H. Detection of chrysotile asbestos in workers urine. United States. https://doi.org/10.1080/15298668591394581
Finn, M B, and Hallenbeck, W H. 1985.
"Detection of chrysotile asbestos in workers urine". United States. https://doi.org/10.1080/15298668591394581.
@article{osti_5147377,
title = {Detection of chrysotile asbestos in workers urine},
author = {Finn, M B and Hallenbeck, W H},
abstractNote = {Urinary asbestos concentrations were evaluated as an indicator of occupational exposure to chrysotile asbestos via inhalation and ingestion. Detection of asbestos in the urine represents the first step in developing a biological indicator of exposure. Such an indicator could be used to supplement exposure data from workplace air sampling. A biological indicator would be particularly valuable in evaluating workers with intermittent airborne asbestos exposures and in determining if airborne exposure results in penetration of asbestos through the lung or gastro-intestinal tract. Transmission electron microscopy was selected as the most sensitive technique for identification of all sizes of asbestos fibers which might appear in the urine. The levels of chrysotile asbestos detected in the urine of five workers were significantly greater than the asbestos concentrations in matched field blanks. Also, the workers urinary asbestos levels were significantly greater than the concentrations found in the control group. Finally, the levels of chrysotile asbestos detected in the urine of two of six controls were significantly greater than those in matched field blanks. Although the project was not specifically designed to correlate urinary and airborne asbestos concentrations, preliminary data indicated that a correlation did not exist between these factors.},
doi = {10.1080/15298668591394581},
url = {https://www.osti.gov/biblio/5147377},
journal = {Am. Ind. Hyg. Assoc. J.; (United States)},
number = ,
volume = 3,
place = {United States},
year = {Fri Mar 01 00:00:00 EST 1985},
month = {Fri Mar 01 00:00:00 EST 1985}
}