Accumulation and toxicokinetics of fluoranthene in water-only exposures with freshwater amphipods
- National Oceanic and Atmospheric Administration, Ann Arbor, MI (United States). Great Lakes Environmental Research Lab.
Two 10-d water-only toxicity tests with radiolabeled fluoranthene were conducted with two species of freshwater amphipods, Hyalella azteca and Diporeia sp. For H. azteca, 10-d median lethal concentrations were 564 nmol/L and 481 nmol/L. Tentative median lethal doses, determined from the regressions of body burden of remaining live H. azteca versus survival, were 5.6 and 3.6 mmol fluoranthene/kg wet weight tissue. Diporeia appeared to be less sensitive, because survival in Diporeia was greater than 84% after 10-d exposures. Elimination rates determined for Diporeia, ranging from 0.0011 to 0.0042/h were much slower than rates determined for H. azteca of 0.128 to 0.188/h. Faster elimination in H. azteca may be related to its greater ability to metabolize fluoranthene. For H. azteca, an average of 17% of its body burden was present as metabolites after 24 h of exposure to radiolabeled fluoranthene, as compared to 5% for Diporeia. For Diporeia, exposure to various water concentrations of fluoranthene for various lengths of time resulted in declines in the conditional uptake clearance rates. A similar, although less dramatic trend was observed for conditional uptake clearance rates in H. azteca.
- Sponsoring Organization:
- Environmental Protection Agency, Washington, DC (United States); National Oceanic and Atmospheric Administration, Washington, DC (United States)
- OSTI ID:
- 514521
- Journal Information:
- Environmental Toxicology and Chemistry, Vol. 16, Issue 4; Other Information: PBD: Apr 1997
- Country of Publication:
- United States
- Language:
- English
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