Central nervous system malformations in relation to two polyvinyl chloride production facilities

Journal Article · Fri Sep 01 00:00:00 EDT 1989 · Archives of Environmental Health; (USA)

DOI:https://doi.org/10.1080/00039896.1989.9935894· OSTI ID:5128533

Rosenman, K D; Rizzo, J E; Conomos, M G; Halpin, G J ^[1]

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1. New Jersey Department of Health, Trenton (USA)

A modified case-control study was conducted for selected birth defects that occurred among residents who lived in areas that surrounded two vinyl chloride polymerization facilities in New Jersey. Odds ratios for central nervous system defects (ICD 9, 740-742) decreased as the distance the mothers' residences were located from the facilities increased. Higher odds ratios for central nervous system birth defects were found in the areas around the plant that had higher vinyl chloride emissions. None of the odds ratios, however, were statistically significant. The differences in concentrations of emissions from the different plants may contribute to the discrepancies reported in previous studies wherein the risk of environmental exposure to vinyl chloride was assessed.

• OSTI ID: 5128533
• Journal Information: Archives of Environmental Health; (USA), Vol. 44:5; ISSN 0003-9896
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
NERVOUS SYSTEM DISEASES
EPIDEMIOLOGY
PVC
TERATOGENESIS
AIR POLLUTION
CENTRAL NERVOUS SYSTEM
CONGENITAL DISEASES
DOSE-RESPONSE RELATIONSHIPS
ENVIRONMENTAL EXPOSURE
INFANTS
MAN
NEW JERSEY
RISK ASSESSMENT
AGE GROUPS
ANIMALS
CHILDREN
CHLORINATED ALIPHATIC HYDROCARBONS
DISEASES
FEDERAL REGION II
HALOGENATED ALIPHATIC HYDROCARBONS
MAMMALS
NERVOUS SYSTEM
NORTH AMERICA
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC POLYMERS
POLLUTION
POLYMERS
POLYVINYLS
PRIMATES
USA
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology