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Title: Miniaturized flow injection analysis system

A chemical analysis technique known as flow injection analysis is described, wherein small quantities of chemical reagents and sample are intermixed and reacted within a capillary flow system and the reaction products are detected optically, electrochemically, or by other means. A highly miniaturized version of a flow injection analysis system has been fabricated utilizing microfabrication techniques common to the microelectronics industry. The microflow system uses flow capillaries formed by etching microchannels in a silicon or glass wafer followed by bonding to another wafer, commercially available microvalves bonded directly to the microflow channels, and an optical absorption detector cell formed near the capillary outlet, with light being both delivered and collected with fiber optics. The microflow system is designed mainly for analysis of liquids and currently measures 38{times}25{times}3 mm, but can be designed for gas analysis and be substantially smaller in construction. 9 figs.
Authors:
Publication Date:
OSTI Identifier:
512409
Report Number(s):
US 5,644,395/A/
PAN: US patent application 8-502,795
DOE Contract Number:
W-7405-ENG-48
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 1 Jul 1997
Research Org:
University of California
Sponsoring Org:
USDOE, Washington, DC (United States)
Country of Publication:
United States
Language:
English
Subject:
40 CHEMISTRY; CHEMICAL ANALYSIS; MINIATURIZATION; MEASURING INSTRUMENTS; DESIGN; OPERATION; LIQUIDS; GAS ANALYSIS; VISIBLE RADIATION; ABSORPTION