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Title: Short-lived positron emitter labeled radiotracers - present status

The preparation of labelled compounds is important for the application of positron emission transaxial tomography (PETT) in biomedical sciences. This paper describes problems and progress in the synthesis of short-lived positron emitter (/sup 11/C, /sup 18/F, /sup 13/N) labelled tracers for PETT. Synthesis of labelled sugars, amino acids, and neurotransmitter receptors (pimozide and spiroperidol tagged with /sup 11/C) is discussed in particular. (DLC)
Authors:
;
Publication Date:
OSTI Identifier:
5104822
Report Number(s):
BNL-31713; CONF-820666-7
ON: DE82020526
DOE Contract Number:
AC02-76CH00016
Resource Type:
Conference
Resource Relation:
Conference: International symposium on the synthesis and applications of isotopically labeled compounds, Kansas City, MO, USA, 6 Jun 1982
Research Org:
Brookhaven National Lab., Upton, NY (USA)
Country of Publication:
United States
Language:
English
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; 62 RADIOLOGY AND NUCLEAR MEDICINE; AMINO ACIDS; LABELLING; CARBON 11; ISOTOPIC EXCHANGE; FLUORINE 18; LABELLED COMPOUNDS; SYNTHESIS; NITROGEN 13; SACCHARIDES; BETA-PLUS DECAY; TOMOGRAPHY; TRACER TECHNIQUES; BETA DECAY; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBOHYDRATES; CARBON ISOTOPES; CARBOXYLIC ACIDS; DECAY; DIAGNOSTIC TECHNIQUES; ELECTRON CAPTURE RADIOISOTOPES; EVEN-ODD NUCLEI; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; LIGHT NUCLEI; MINUTES LIVING RADIOISOTOPES; NITROGEN ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; RADIOISOTOPES 400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials; 550601 -- Medicine-- Unsealed Radionuclides in Diagnostics