Luteinizing hormone receptors in human ovarian follicles and corpora lutea during the menstrual cycle

Journal Article · Fri Aug 01 00:00:00 EDT 1986 · Obstet. Gynecol.; (United States)

OSTI ID:5092974

Yamoto, M; Nakano, R; Iwasaki, M; Ikoma, H; Furukawa, K

The binding of /sup 125/I-labeled human luteinizing hormone (hLH) to the 2000-g fraction of human ovarian follicles and corpora lutea during the entire menstrual cycle was examined. Specific high affinity, low capacity receptors for hLH were demonstrated in the 2000-g fraction of both follicles and corpora lutea. Specific binding of /sup 125/I-labeled hLH to follicular tissue increased from the early follicular phase to the ovulatory phase. Specific binding of /sup 125/I-labeled hLH to luteal tissue increased from the early luteal phase to the midluteal phase and decreased towards the late luteal phase. The results of the present study indicate that the increase and decrease in receptors for hLH during the menstrual cycle might play an important role in the regulation of the ovarian cycle.

• Research Organization: Wakayama Medical College, Japan
• OSTI ID: 5092974
• Journal Information: Obstet. Gynecol.; (United States), Vol. 2
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
LH
RADIORECEPTOR ASSAY
MENSTRUAL CYCLE
PHYSIOLOGY
IODINE 125
LABELLED COMPOUNDS
RECEPTORS
BETA DECAY RADIOISOTOPES
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
GONADOTROPINS
HORMONES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MEMBRANE PROTEINS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
PEPTIDE HORMONES
PITUITARY HORMONES
PROTEINS
RADIOISOTOPES
TRACER TECHNIQUES
551001* - Physiological Systems- Tracer Techniques