Fatal radiation hepatitis: a case report and review of the literature

Journal Article · Tue Jul 01 00:00:00 EDT 1986 · Gynecol. Oncol.; (United States)

DOI:https://doi.org/10.1016/0090-8258(86)90316-1· OSTI ID:5091240

Schacter, L; Crum, E; Spitzer, T; Maksem, J; Diwan, V; Kolli, S

A case of fatal radiation hepatitis occurring after treatment with 2200 rad given by the moving strip technique is presented. This fatality occurred in a 28-year-old woman with persistent ovarian carcinoma despite prolonged chemotherapy. Scans of the liver using computerized tomography, /sup 99m/Tc sulfur colloid, and /sup 99m/Tc diisopropyl iminodiacetic acid showed abnormalities only in sulfur colloid uptake and these resolved late in the course. Death was caused by progressive hepatic and renal failure. Postmortem examination showed changes typical of radiation hepatitis. Only 32 cases of radiation hepatitis have been previously reported and they are reviewed. The possible role of prolonged prior chemotherapy in enhancing sensitivity to radiotherapy is considered.

• OSTI ID: 5091240
• Journal Information: Gynecol. Oncol.; (United States), Vol. 3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
HEPATITIS
RADIOINDUCTION
LIVER
BIOLOGICAL RADIATION EFFECTS
RADIOTHERAPY
SIDE EFFECTS
AUTOPSY
CARCINOMAS
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DISEASES
GLANDS
INJURIES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIOLOGY
THERAPY
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