Procarbazine-induced interstitial pneumonitis with a normal chest x-ray: a case report

Journal Article · Wed Jan 01 00:00:00 EST 1986 · Med. Pediatr. Oncol.; (United States)

DOI:https://doi.org/10.1002/mpo.2950140411· OSTI ID:5072859

Garbes, I D; Henderson, E S; Gomez, G A; Bakshi, S P; Parthasarathy, K L; Castillo, N B

Pulmonary toxicity due to cytotoxic drugs is well described in the literature. This is most commonly described in association with bleomycin, busulfan, and methotrexate. This report presents a case of interstitial pneumonitis with a normal chest x-ray that is most certainly due to procarbazine. In addition, the role of gallium-67 citrate scintigraphy in early diagnosis is discussed. This is especially important since discontinuation of the drug before radiographic manifestations of pulmonary toxicity become evident may prevent permanent pulmonary injury and its sequelae.

• Research Organization: Roswell Park Memorial Institute, Buffalo, NY
• OSTI ID: 5072859
• Journal Information: Med. Pediatr. Oncol.; (United States), Vol. 4
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CHEMOTHERAPY
SIDE EFFECTS
PNEUMONITIS
DIAGNOSIS
GALLIUM 67
LUNGS
SCINTISCANNING
BETA DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATORY SYSTEM
THERAPY
550601* - Medicine- Unsealed Radionuclides in Diagnostics