CBF before and after extracranial-intracranial bypass surgery in patients with ischemic cerebrovascular disease studied with /sup 133/Xe-inhalation tomography
Cerebral blood flow (CBF) was studied by /sup 133/Xenon inhalation tomography in 22 patients with symptoms of ischemic cerebrovascular disease before and after establishment of an extracranial-intracranial bypass shunt. Selection of patients for shunting was based on angiographically demonstrated arterial occlusions and on the finding of focal low flow areas corresponding to the clinical symptoms, that consisted mainly of minor stroke with good remission and with or without subsequent TIAs. It was required that the area of low flow should clearly exceed the CT lesion present in practically all cases. Following surgery, the permanent neurologic deficits remained unchanged, while the TIAs stopped in all but one case. Two patients showed a definite increase of CBF in the low flow area while another two showed a questionable increase. All the other cases, 18 of the 22, showed an unchanged tomographic flow map with no trend towards diminution in extension or severity of the focal hypoperfused area. A persistent low flow in areas with no corresponding CT lesion following alleviation of a possible flow impediment is interpreted to represent an incomplete infarction or diaschisis.
- Research Organization:
- Rigshospitalet, Copenhagen, Denmark
- OSTI ID:
- 5020380
- Journal Information:
- Stroke; (United States), Vol. 4
- Country of Publication:
- United States
- Language:
- English
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BRAIN
BLOOD FLOW
ISCHEMIA
DIAGNOSIS
EMISSION COMPUTED TOMOGRAPHY
PATIENTS
SURGERY
XENON 133
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR DISEASES
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
EVEN-ODD NUCLEI
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NERVOUS SYSTEM
NUCLEI
ORGANS
RADIOISOTOPES
TOMOGRAPHY
VASCULAR DISEASES
XENON ISOTOPES
550600* - Medicine
550601 - Medicine- Unsealed Radionuclides in Diagnostics