Effect of coronary artery recanalization on right ventricular function in patients with acute myocardial infarction

Journal Article · Wed May 01 00:00:00 EDT 1985 · J. Am. Coll. Cardiol.; (United States)

DOI:https://doi.org/10.1016/S0735-1097(85)80002-4· OSTI ID:5018299

Verani, M S; Tortoledo, F E; Batty, J W; Raizner, A E

The effects of coronary artery recanalization by intracoronary administration of streptokinase on left ventricular function during acute myocardial infarction have received increasing attention in recent years. Although myocardial dysfunction is often more pronounced in the right ventricle than in the left ventricle in patients with acute inferior wall myocardial infarction, the effect of coronary artery recanalization on right ventricular dysfunction has not been previously addressed. Accordingly, in this investigation, 54 patients who participated in a prospective, controlled, randomized trial of recanalization during acute myocardial infarction were studied. Among 30 patients with inferior wall infarction, 19 had right ventricular dysfunction on admission; 11 of these 19 had positive uptake of technetium-99m pyrophosphate in the right ventricle, indicative of right ventricular infarction. Patients with successful recanalization exhibited improved right ventricular ejection fraction from admission to day 10. However, control patients and patients who did not undergo recanalization also exhibited improvement. These data indicate that the right ventricular dysfunction commonly associated with inferior wall infarction is often transient, and improvement is the rule, irrespective of early recanalization of the infarct vessel.

• Research Organization: Baylor College of Medicine, Houston, TX
• OSTI ID: 5018299
• Journal Information: J. Am. Coll. Cardiol.; (United States), Vol. 5
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
HEART
CHEMOTHERAPY
TECHNETIUM 99
UPTAKE
CORONARIES
ISOMERIC NUCLEI
MYOCARDIAL INFARCTION
PATIENTS
PYROPHOSPHATES
STREPTOCOCCAL PROTEINASE
ARTERIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD VESSELS
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
DISEASES
ENZYMES
HOURS LIVING RADIOISOTOPES
HYDROLASES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PEPTIDE HYDROLASES
PHOSPHORUS COMPOUNDS
RADIOISOTOPES
SH-PROTEINASES
TECHNETIUM ISOTOPES
THERAPY
YEARS LIVING RADIOISOTOPES
551001* - Physiological Systems- Tracer Techniques
550601 - Medicine- Unsealed Radionuclides in Diagnostics