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Title: Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system

Abstract

The purpose of this study was to evaluate CT arteriography (CTA) using an implantable port system in the detection of perfusion abnormalities occurring during hepatic arterial infusion chemotherapy (HAIC). In 51 patients with unresectable primary and metastatic liver tumors, who had implanted port systems for HAIC, CTA examinations through the infusion pump were performed. When perfusion abnormalities were found, selective angiography and/or digital subtraction angiography using the implantable port system were performed to determine the etiology. Forty-nine perfusion abnormalities were detected in 32 patients. Intrahepatic hypoperfusion was found in 24 cases. Of 11 patients in whom correction of the hypoperfusion was attempted, it was successful in 10. Of 13 patients in whom correction was not attempted, 6 patients showed progressive disease in nonperfused areas. Intrahepatic hyperperfusion was found in 14 cases, which showed no subsequent complication. Extrahepatic perfusion was found in 11 cases. We consider CTA to be useful in detecting perfusion abnormalities that may compromise HAIC. 22 refs., 3 figs., 3 tabs.

Authors:
; ; ;  [1]
  1. Niigata Univ. School of Medicine (Japan); and others
Publication Date:
OSTI Identifier:
457531
Resource Type:
Journal Article
Journal Name:
Journal of Computer Assisted Tomography
Additional Journal Information:
Journal Volume: 20; Journal Issue: 3; Other Information: PBD: May-Jun 1996
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; 44 INSTRUMENTATION, INCLUDING NUCLEAR AND PARTICLE DETECTORS; LIVER; COMPUTERIZED TOMOGRAPHY; CHEMOTHERAPY; NEOPLASMS; ARTERIES

Citation Formats

Seki, Hiroshi, Kimura, Motomasa, Kamura, Takeshi, and Miura, Tsutomu. Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system. United States: N. p., 1996. Web. doi:10.1097/00004728-199605000-00002.
Seki, Hiroshi, Kimura, Motomasa, Kamura, Takeshi, & Miura, Tsutomu. Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system. United States. https://doi.org/10.1097/00004728-199605000-00002
Seki, Hiroshi, Kimura, Motomasa, Kamura, Takeshi, and Miura, Tsutomu. 1996. "Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system". United States. https://doi.org/10.1097/00004728-199605000-00002.
@article{osti_457531,
title = {Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system},
author = {Seki, Hiroshi and Kimura, Motomasa and Kamura, Takeshi and Miura, Tsutomu},
abstractNote = {The purpose of this study was to evaluate CT arteriography (CTA) using an implantable port system in the detection of perfusion abnormalities occurring during hepatic arterial infusion chemotherapy (HAIC). In 51 patients with unresectable primary and metastatic liver tumors, who had implanted port systems for HAIC, CTA examinations through the infusion pump were performed. When perfusion abnormalities were found, selective angiography and/or digital subtraction angiography using the implantable port system were performed to determine the etiology. Forty-nine perfusion abnormalities were detected in 32 patients. Intrahepatic hypoperfusion was found in 24 cases. Of 11 patients in whom correction of the hypoperfusion was attempted, it was successful in 10. Of 13 patients in whom correction was not attempted, 6 patients showed progressive disease in nonperfused areas. Intrahepatic hyperperfusion was found in 14 cases, which showed no subsequent complication. Extrahepatic perfusion was found in 11 cases. We consider CTA to be useful in detecting perfusion abnormalities that may compromise HAIC. 22 refs., 3 figs., 3 tabs.},
doi = {10.1097/00004728-199605000-00002},
url = {https://www.osti.gov/biblio/457531}, journal = {Journal of Computer Assisted Tomography},
number = 3,
volume = 20,
place = {United States},
year = {Wed May 01 00:00:00 EDT 1996},
month = {Wed May 01 00:00:00 EDT 1996}
}