Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system
Abstract
The purpose of this study was to evaluate CT arteriography (CTA) using an implantable port system in the detection of perfusion abnormalities occurring during hepatic arterial infusion chemotherapy (HAIC). In 51 patients with unresectable primary and metastatic liver tumors, who had implanted port systems for HAIC, CTA examinations through the infusion pump were performed. When perfusion abnormalities were found, selective angiography and/or digital subtraction angiography using the implantable port system were performed to determine the etiology. Forty-nine perfusion abnormalities were detected in 32 patients. Intrahepatic hypoperfusion was found in 24 cases. Of 11 patients in whom correction of the hypoperfusion was attempted, it was successful in 10. Of 13 patients in whom correction was not attempted, 6 patients showed progressive disease in nonperfused areas. Intrahepatic hyperperfusion was found in 14 cases, which showed no subsequent complication. Extrahepatic perfusion was found in 11 cases. We consider CTA to be useful in detecting perfusion abnormalities that may compromise HAIC. 22 refs., 3 figs., 3 tabs.
- Authors:
-
- Niigata Univ. School of Medicine (Japan); and others
- Publication Date:
- OSTI Identifier:
- 457531
- Resource Type:
- Journal Article
- Journal Name:
- Journal of Computer Assisted Tomography
- Additional Journal Information:
- Journal Volume: 20; Journal Issue: 3; Other Information: PBD: May-Jun 1996
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; 44 INSTRUMENTATION, INCLUDING NUCLEAR AND PARTICLE DETECTORS; LIVER; COMPUTERIZED TOMOGRAPHY; CHEMOTHERAPY; NEOPLASMS; ARTERIES
Citation Formats
Seki, Hiroshi, Kimura, Motomasa, Kamura, Takeshi, and Miura, Tsutomu. Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system. United States: N. p., 1996.
Web. doi:10.1097/00004728-199605000-00002.
Seki, Hiroshi, Kimura, Motomasa, Kamura, Takeshi, & Miura, Tsutomu. Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system. United States. https://doi.org/10.1097/00004728-199605000-00002
Seki, Hiroshi, Kimura, Motomasa, Kamura, Takeshi, and Miura, Tsutomu. 1996.
"Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system". United States. https://doi.org/10.1097/00004728-199605000-00002.
@article{osti_457531,
title = {Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system},
author = {Seki, Hiroshi and Kimura, Motomasa and Kamura, Takeshi and Miura, Tsutomu},
abstractNote = {The purpose of this study was to evaluate CT arteriography (CTA) using an implantable port system in the detection of perfusion abnormalities occurring during hepatic arterial infusion chemotherapy (HAIC). In 51 patients with unresectable primary and metastatic liver tumors, who had implanted port systems for HAIC, CTA examinations through the infusion pump were performed. When perfusion abnormalities were found, selective angiography and/or digital subtraction angiography using the implantable port system were performed to determine the etiology. Forty-nine perfusion abnormalities were detected in 32 patients. Intrahepatic hypoperfusion was found in 24 cases. Of 11 patients in whom correction of the hypoperfusion was attempted, it was successful in 10. Of 13 patients in whom correction was not attempted, 6 patients showed progressive disease in nonperfused areas. Intrahepatic hyperperfusion was found in 14 cases, which showed no subsequent complication. Extrahepatic perfusion was found in 11 cases. We consider CTA to be useful in detecting perfusion abnormalities that may compromise HAIC. 22 refs., 3 figs., 3 tabs.},
doi = {10.1097/00004728-199605000-00002},
url = {https://www.osti.gov/biblio/457531},
journal = {Journal of Computer Assisted Tomography},
number = 3,
volume = 20,
place = {United States},
year = {Wed May 01 00:00:00 EDT 1996},
month = {Wed May 01 00:00:00 EDT 1996}
}