Induced histopathologic alterations in early life stages (ELS) of medaka (Oryzias latipes)
- Univ. of California, Davis, CA (United States)
Agricultural and industrial pollutants cause extensive alterations in fish embryos, and the cardiovascular system is often targeted. Dioxin and dioxin-like compounds produce lesions in lake and rainbow trout (Salvelinus namaycush and Oncorhynchus mykiss), and northern pike (Esox lucius), ultimately compromising ELS survival, and possibly stock recruitment. Pericardial edema was produced by exposure of medaka embryos to thiobencarb, molinate, 1,3-dinitrobenzene, dioxin, and products of incomplete combustion from trichloroethylene incineration. These lesions closely resembled those observed in birds, Xenopus, and other fish species. This work focuses on gross morphologic and histologic alterations of heart, major blood vessels, pericardial cavity, skeletal muscle, and brain. Endothelium, perivascular connective tissue, and other tissues of embryos and larvae were examined in semithin (4 {mu}m) glycolmethacrylate-embedded serial sections. Structural defects and their microscopic features will be presented.
- OSTI ID:
- 40093
- Report Number(s):
- CONF-9410273-; TRN: IM9520%%288
- Resource Relation:
- Conference: 15. annual meeting of the Society of Environmental Toxicology and Chemistry (SETAC), Denver, CO (United States), 30 Oct - 3 Nov 1994; Other Information: PBD: 1994; Related Information: Is Part Of Society of Environmental Toxicology and Chemistry 15th annual meeting: Abstract book. Ecological risk: Science, policy, law, and perception; PB: 286 p.
- Country of Publication:
- United States
- Language:
- English
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