Deterministic effects of {sup 241}Am exposure in the Hanford americium accident case

Journal Article · Fri Sep 01 00:00:00 EDT 1995 · Health Physics

DOI:https://doi.org/10.1097/00004032-199509000-00005· OSTI ID:229659

Filipy, R E; Toohey, R E; Kathren, R L; Dietert, S E ^[1]

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1. Washington State Univ., Richland, WA (United States)

Lifetime follow-up of USTUR Case 246 demonstrated the lack of severe biological effects resulting from his exposure to {sup 241}Am. Deterministic effects observed were limited to hematological changes, including lymphopenia and thrombocytopenia. These hematological changes were consistent with those observed in experimental animals following actinide exposure. Cataracts were removed from the left and right eyes at 547, and 1,030 d after the accident, respectively, but were considered to be trauma-induced rather than radiation-induced. No abnormal findings were reported from gross of histological examinations of tissue samples removed at autopsy, other than those resulting from the subject`s pre-existing cardiovascular disease. 30 refs., 7 figs., 1 tab.

• Sponsoring Organization: USDOE
• OSTI ID: 229659
• Journal Information: Health Physics, Vol. 69, Issue 3; Other Information: PBD: Sep 1995
• Country of Publication: United States
• Language: English

Related Subjects

56 BIOLOGY AND MEDICINE
APPLIED STUDIES
55 BIOLOGY AND MEDICINE
BASIC STUDIES
AMERICIUM 241
TISSUE DISTRIBUTION
INHALATION
SKIN ABSORPTION
MAN
BIOLOGICAL RADIATION EFFECTS
HANFORD RESERVATION
RADIATION ACCIDENTS
DOSIMETRY
OCCUPATIONAL EXPOSURE
AUTOPSY
DECONTAMINATION
ACUTE EXPOSURE
DOSE RATES
PATHOLOGY
CATARACTS
LYMPHOPENIA