The life science x-ray scattering beamline at NSLS-II

Journal Article · Wed Jul 27 00:00:00 EDT 2016 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.4952872· OSTI ID:22608385

DiFabio, Jonathan; Chodankar, Shirish; Pjerov, Sal; Jakoncic, Jean; Lucas, Michael; Graziano, Vito; Yang, Lin ^[1]; Krywka, Christina ^[1]

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1. National Synchrotron Light Source II, Brookhaven National Laboratory, Upton, New York (United States)

We report the current development status of the High Brightness X-ray Scattering for Life Sciences (or Life Science X-ray Scattering, LiX) beamline at the NSLS-II facility of Brookhaven National Laboratory. This instrument will operate in the x-ray energy range of 2.1-18 keV, provide variable beam sizes from 1 micron to ∼0.5 mm, and support user experiments in three scientific areas: (1) high-throughput solution scattering, in-line size exclusion chromatography and flow mixers-based time-resolved solution scattering of biological macro-molecules, (2) diffraction from single- and multi-layered lipid membranes, and (3) scattering-based scanning probe imaging of biological tissues. In order to satisfy the beam stability required for these experiments and to switch rapidly between different types of experiments, we have adopted a secondary source with refractive lenses for secondary focusing, a detector system consisting of three Pilatus detectors, and specialized experimental modules that can be quickly exchanged and each dedicated to a defined set of experiments. The construction of this beamline is on schedule for completion in September 2015. User experiments are expected to start in Spring 2016.

• OSTI ID: 22608385
• Journal Information: AIP Conference Proceedings, Vol. 1741, Issue 1; Conference: SRI2015: 12. international conference on synchrotron radiation instrumentation, New York, NY (United States), 6-10 Jul 2015; Other Information: (c) 2016 Author(s); Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

43 PARTICLE ACCELERATORS
ANIMAL TISSUES
BEAMS
BIOMEDICAL RADIOGRAPHY
BNL
FOCUSING
KEV RANGE
LENSES
MEMBRANES
MOLECULES
NSLS
STABILITY
SWITCHES
TIME RESOLUTION
X RADIATION
X-RAY DIFFRACTION