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Title: Effect of silver additive on physicochemical properties of hydroxyapatite applied to reconstructive surgery

The effect of silver adding to hydroxyapatite (HA) in its solubility in physiological solution and biological activity was investigated. Samples of HA containing silver (AgHA) obtained by liquid-phase method in the conditions of microwave exposure. Solubility (C{sub Ca}{sup 2+}·10{sup 3}, mol/l) of the powders AgHA was determined by chemical methods according trilonometric titration of the calcium ions in physiological solution at 25 and 37 °C. To investigate the biological activity of the samples, a series of experiments on the formation of the calcium-phosphate layer on the surface of the SBF-solution at 37 °C for 28 days. Electronic micrographs of samples taken at the end of each 7 days of the experiment, indicate the formation of calcium-phosphate layer (CPL) in the samples, the kinetics of which is shown as a function of cumulative concentrations of calcium and magnesium ions from time.
Authors:
; ;  [1]
  1. National Research Tomsk State University 36, Lenina Avenue, Tomsk, 634050 (Russian Federation)
Publication Date:
OSTI Identifier:
22496172
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1688; Journal Issue: 1; Conference: NEWOT'2015: 5. international scientific conference on new operational technologies, Tomsk (Russian Federation), 29-30 Sep 2015; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; ADDITIVES; APATITES; CALCIUM; CALCIUM IONS; CALCIUM PHOSPHATES; CONCENTRATION RATIO; DIAGRAMS; LAYERS; LIQUIDS; MAGNESIUM IONS; MICROWAVE RADIATION; POWDERS; SILVER; SOLUBILITY; SURGERY; TITRATION