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Title: Structural properties of a bone-ceramic composite as a promising material in spinal surgery

The paper describes the results of in vitro tests of composite bone-ceramic implants and procedures for modifying implant surfaces to enhance osteogenesis. Analysis of CBCI ESs demonstrated that they have a porous structure with the mean longitudinal pore size of 70 µm and the mean transverse pore size of 46 µm; surface pores are open, while inner pores are closed. Elemental analysis of the CBCI surface demonstrates that CBCIs are composed of aluminum and zirconium oxides and contain HA inclusions. Profilometry of the CBCI ES surface revealed the following deviations: the maximum deviation of the profile in the sample center is 15 µm and 16 µm on the periphery, while the arithmetical mean and mean square deviations of the profile are 2.65 and 3.4 µm, respectively. In addition, CBCI biodegradation products were pre-examined; a 0.9% NaCl solution was used as a comparison group. Potentially toxic and tissue accumulated elements, such as cadmium, cobalt, mercury, and lead, are present only in trace amounts and have no statistically significant differences with the comparison group, which precludes their potential toxic effects on the macroorganism. Ceramic-based CBCI may be effective and useful in medicine for restoration of the anatomic integrity and functions of the bone tissue.
Authors:
; ; ;  [1] ; ;  [2] ;  [3]
  1. Novosibirsk Research Institute of Traumatology and Orthopedics n.a. Ya.L. Tsivyan, Novosibirsk (Russian Federation)
  2. Christianovich Institute of Theoretical and Applied Mechanics, SB RAS, Novosibirsk (Russian Federation)
  3. Institute of Solid State Chemistry and Mechanochemistry, SB RAS, Novosibirsk (Russian Federation)
Publication Date:
OSTI Identifier:
22496171
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1688; Journal Issue: 1; Conference: NEWOT'2015: 5. international scientific conference on new operational technologies, Tomsk (Russian Federation), 29-30 Sep 2015; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; ALUMINIUM OXIDES; BIODEGRADATION; BONE TISSUES; CADMIUM; CERAMICS; COBALT; COMPARATIVE EVALUATIONS; IMPLANTS; LEAD; MERCURY; POROUS MATERIALS; SKELETON; SODIUM CHLORIDES; SURFACES; SURGERY; TOXICITY; TRACE AMOUNTS; ZIRCONIUM OXIDES