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Title: Development of a phase-sensitive Fourier domain optical coherence tomography system to measure mouse organ of Corti vibrations in two cochlear turns

In this study, we have developed a phase-sensitive Fourier-domain optical coherence tomography system to simultaneously measure the in vivo inner ear vibrations in the hook area and second turn of the mouse cochlea. This technical development will enable measurement of intra-cochlear distortion products at ideal locations such as the distortion product generation site and reflection site. This information is necessary to un-mix the complex mixture of intra-cochlear waves comprising the DPOAE and thus leads to the non-invasive identification of the local region of cochlear damage.
Authors:
 [1] ; ;  [2] ; ;  [3] ;  [1] ;  [4]
  1. Oregon Hearing Research Center, Oregon Health & Science University, Portland, Oregon (United States)
  2. Department of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon (United States)
  3. Department of Bioengineering, University of Washington, Seattle, Washington (United States)
  4. (United States)
Publication Date:
OSTI Identifier:
22494508
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1703; Journal Issue: 1; Conference: 12. international workshop on the mechanics of hearing, Cape Sounio (Greece), 23-29 Jun 2014; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; AUDITORY ORGANS; DAMAGE; IN VIVO; MICE; OPTICAL EQUIPMENT; REFLECTION; TOMOGRAPHY