skip to main content

SciTech ConnectSciTech Connect

Title: The second filter’s second coming

We measured sound-evoked vibrations at the stereociliary side of inner and outer hair cells and their surrounding supporting cells, using optical coherence tomography interferometry in living anesthetized guinea pigs. Our measurements demonstrate a gradient in frequency tuning among different cell types, going from a high best frequency at the inner hair cells to a lower one at the Hensen cells. This causes the locus of maximum inner hair cell activation to be shifted toward the apex of the cochlea as compared to the outer hair cells. These observations show that additional processing and filtering of acoustic signals occurs within the organ of Corti prior to inner hair cell excitation, thus reinstating a transformed second filter as a mechanism contributing to cochlear frequency tuning.
Authors:
; ; ;  [1] ;  [1] ;  [2] ;  [1] ;  [2] ;  [3] ;  [1] ;  [4]
  1. Oregon Health & Science University, Portland, Oregon (United States)
  2. (China)
  3. University of Washington, Seattle, Washington (United States)
  4. (Sweden)
Publication Date:
OSTI Identifier:
22494504
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1703; Journal Issue: 1; Conference: 12. international workshop on the mechanics of hearing, Cape Sounio (Greece), 23-29 Jun 2014; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; COMPARATIVE EVALUATIONS; EXCITATION; FILTERS; GUINEA PIGS; HAIR; INTERFEROMETRY; SIGNALS; SOUND WAVES; TOMOGRAPHY; TUNING