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Title: Noninvasive micromanipulation of live HIV-1 infected cells via laser light

Live mammalian cells from various tissues of origin can be aseptically and noninvasively micromanipulated via lasers of different regimes. Laser-driven techniques are therefore paving a path toward the advancement of human immuno-deficiency virus (HIV-1) investigations. Studies aimed at the interaction of laser light, nanomaterials, and biological materials can also lead to an understanding of a wealth of disease conditions and result in photonics-based therapies and diagnostic tools. Thus, in our research, both continuous wave and pulsed lasers operated at varying wavelengths are employed, as they possess special properties that allow classical biomedical applications. This paper discusses photo-translocation of antiretroviral drugs into HIV-1 permissive cells and preliminary results of low-level laser therapy (LLLT) in HIV-1 infected cells.
Authors:
 [1]
  1. National Laser Centre, Council for Scientific and Industrial Research, Pretoria (South Africa)
Publication Date:
OSTI Identifier:
22494409
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1697; Journal Issue: 1; Conference: 5. IUPAP international conference on women in physics, Waterloo (Canada), 5-8 Aug 2014; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; 46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; 63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; AIDS VIRUS; ANIMAL TISSUES; BIOLOGICAL MATERIALS; DIAGNOSTIC TECHNIQUES; DRUGS; HUMAN POPULATIONS; LASER RADIATION; LASERS; NANOMATERIALS; THERAPY; WAVELENGTHS