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Title: SU-E-I-01: Iterative CBCT Reconstruction with a Feature-Preserving Penalty

Purpose: Low-dose CBCT is desired in various clinical applications. Iterative image reconstruction algorithms have shown advantages in suppressing noise in low-dose CBCT. However, due to the smoothness constraint enforced during the reconstruction process, edges may be blurred and image features may lose in the reconstructed image. In this work, we proposed a new penalty design to preserve image features in the image reconstructed by iterative algorithms. Methods: Low-dose CBCT is reconstructed by minimizing the penalized weighted least-squares (PWLS) objective function. Binary Robust Independent Elementary Features (BRIEF) of the image were integrated into the penalty of PWLS. BRIEF is a general purpose point descriptor that can be used to identify important features of an image. In this work, BRIEF distance of two neighboring pixels was used to weigh the smoothing parameter in PWLS. For pixels of large BRIEF distance, weaker smooth constraint will be enforced. Image features will be better preserved through such a design. The performance of the PWLS algorithm with BRIEF penalty was evaluated by a CatPhan 600 phantom. Results: The image quality reconstructed by the proposed PWLS-BRIEF algorithm is superior to that by the conventional PWLS method and the standard FDK method. At matched noise level, edges inmore » PWLS-BRIEF reconstructed image are better preserved. Conclusion: This study demonstrated that the proposed PWLS-BRIEF algorithm has great potential on preserving image features in low-dose CBCT.« less
Authors:
;  [1] ;  [2] ;  [3] ;  [1]
  1. UT Southwestern Medical Center, Dallas, TX (United States)
  2. (China)
  3. Southern Medical University, Guangzhou (China)
Publication Date:
OSTI Identifier:
22486708
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 42; Journal Issue: 6; Other Information: (c) 2015 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; ALGORITHMS; COMPUTERIZED TOMOGRAPHY; IMAGE PROCESSING; IMAGES; ITERATIVE METHODS; LEAST SQUARE FIT; LIMITING VALUES; PHANTOMS; RADIATION DOSES; SMOOTH MANIFOLDS