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Title: Cryogenic molecular separation system for radioactive {sup 11}C ion acceleration

A {sup 11}C molecular production/separation system (CMPS) has been developed as part of an isotope separation on line system for simultaneous positron emission tomography imaging and heavy-ion cancer therapy using radioactive {sup 11}C ion beams. In the ISOL system, {sup 11}CH{sub 4} molecules will be produced by proton irradiation and separated from residual air impurities and impurities produced during the irradiation. The CMPS includes two cryogenic traps to separate specific molecules selectively from impurities by using vapor pressure differences among the molecular species. To investigate the fundamental performance of the CMPS, we performed separation experiments with non-radioactive {sup 12}CH{sub 4} gases, which can simulate the chemical characteristics of {sup 11}CH{sub 4} gases. We investigated the separation of CH{sub 4} molecules from impurities, which will be present as residual gases and are expected to be difficult to separate because the vapor pressure of air molecules is close to that of CH{sub 4}. We determined the collection/separation efficiencies of the CMPS for various amounts of air impurities and found desirable operating conditions for the CMPS to be used as a molecular separation device in our ISOL system.
Authors:
; ; ; ; ; ; ;  [1] ; ; ; ; ;  [2]
  1. National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku Chiba 263–8555 (Japan)
  2. Joint Institute for Nuclear Research, Dubna 141980 (Russian Federation)
Publication Date:
OSTI Identifier:
22482638
Resource Type:
Journal Article
Resource Relation:
Journal Name: Review of Scientific Instruments; Journal Volume: 86; Journal Issue: 12; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; ACCELERATION; AIR; CARBON 11; EFFICIENCY; EQUIPMENT; HEAVY IONS; IMPURITIES; ION BEAMS; IRRADIATION; METHANE; MOLECULES; NEOPLASMS; ON-LINE SYSTEMS; PERFORMANCE; POSITRON COMPUTED TOMOGRAPHY; THERAPY; TRAPS; VAPOR PRESSURE