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Title: Technical Note: Preliminary investigations into the use of a functionalised polymer to reduce diffusion in Fricke gel dosimeters

Purpose: A modification of the existing PVA-FX hydrogel has been made to investigate the use of a functionalised polymer in a Fricke gel dosimetry system to decrease Fe{sup 3+} diffusion. Methods: The chelating agent, xylenol orange, was chemically bonded to the gelling agent, polyvinyl alcohol (PVA) to create xylenol orange functionalised PVA (XO-PVA). A gel was created from the XO-PVA (20% w/v) with ferrous sulfate (0.4 mM) and sulfuric acid (50 mM). Results: This resulted in an optical density dose sensitivity of 0.014 Gy{sup −1}, an auto-oxidation rate of 0.0005 h{sup −1}, and a diffusion rate of 0.129 mm{sup 2} h{sup −1}; an 8% reduction compared to the original PVA-FX gel, which in practical terms adds approximately 1 h to the time span between irradiation and accurate read-out. Conclusions: Because this initial method of chemically bonding xylenol orange to polyvinyl alcohol has inherently low conversion, the improvement on existing gel systems is minimal when compared to the drawbacks. More efficient methods of functionalising polyvinyl alcohol with xylenol orange must be developed for this system to gain clinical relevance.
Authors:
; ; ; ;  [1] ;  [2] ;  [3]
  1. School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology, Brisbane 4000 (Australia)
  2. School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology, Brisbane 4000, Australia and Cancer Care Services, Royal Brisbane and Women’s Hospital, Brisbane 4006 (Australia)
  3. School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology, Brisbane 4000, Australia and Genesis Cancer Care Queensland, Brisbane 4066 (Australia)
Publication Date:
OSTI Identifier:
22482419
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 42; Journal Issue: 12; Other Information: (c) 2015 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; APPROXIMATIONS; CHELATING AGENTS; DOSEMETERS; DOSIMETRY; GELS; PVA; READOUT SYSTEMS; XYLENOL ORANGE