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Title: Multipinhole SPECT helical scan parameters and imaging volume

Purpose: The authors developed SPECT imaging capability on an animal PET scanner using a multiple-pinhole collimator and step-and-shoot helical data acquisition protocols. The objective of this work was to determine the preferred helical scan parameters, i.e., the angular and axial step sizes, and the imaging volume, that provide optimal imaging performance. Methods: The authors studied nine helical scan protocols formed by permuting three rotational and three axial step sizes. These step sizes were chosen around the reference values analytically calculated from the estimated spatial resolution of the SPECT system and the Nyquist sampling theorem. The nine helical protocols were evaluated by two figures-of-merit: the sampling completeness percentage (SCP) and the root-mean-square (RMS) resolution. SCP was an analytically calculated numerical index based on projection sampling. RMS resolution was derived from the reconstructed images of a sphere-grid phantom. Results: The RMS resolution results show that (1) the start and end pinhole planes of the helical scheme determine the axial extent of the effective field of view (EFOV), and (2) the diameter of the transverse EFOV is adequately calculated from the geometry of the pinhole opening, since the peripheral region beyond EFOV would introduce projection multiplexing and consequent effects. The RMS resolution resultsmore » of the nine helical scan schemes show optimal resolution is achieved when the axial step size is the half, and the angular step size is about twice the corresponding values derived from the Nyquist theorem. The SCP results agree in general with that of RMS resolution but are less critical in assessing the effects of helical parameters and EFOV. Conclusions: The authors quantitatively validated the effective FOV of multiple pinhole helical scan protocols and proposed a simple method to calculate optimal helical scan parameters.« less
Authors:
;  [1] ; ; ;  [2] ;  [3]
  1. Department of Nuclear Medicine, State University of New York at Buffalo, Buffalo, New York 14214 (United States)
  2. Department of Engineering Physics, Tsinghua University, Beijing 100084 (China)
  3. Department of Nuclear Medicine and Radiobiology, Sherbrooke Molecular Imaging Center, Université de Sherbrooke, Sherbrooke, Quebec J1H 5N4 (Canada)
Publication Date:
OSTI Identifier:
22482404
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 42; Journal Issue: 11; Other Information: (c) 2015 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 60 APPLIED LIFE SCIENCES; BIOMEDICAL RADIOGRAPHY; COLLIMATORS; DATA ACQUISITION; IMAGES; PHANTOMS; POSITRON COMPUTED TOMOGRAPHY; SAMPLING; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; SPATIAL RESOLUTION