Microwave Ablation (MWA) for the Treatment of a Solitary, Chemorefractory Testicular Cancer Liver Metastasis

Journal Article · Wed Apr 15 00:00:00 EDT 2015 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-014-0924-Z· OSTI ID:22470011

Violari, Elena G., E-mail: [e-mail]; Petre, Elena N., E-mail: [e-mail] ^[1]; Feldman, Darren R., E-mail: [e-mail] ^[2]; Erinjeri, Joseph P., E-mail: [e-mail]; Brown, Karen T., E-mail: [e-mail]; Solomon, Stephen B., E-mail: [e-mail] ^[1]; D’Angelica, Michael I., E-mail: [e-mail] ^[3]; Sofocleous, Constantinos T., E-mail: [e-mail] ^[1]

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1. Memorial Sloan-Kettering Cancer Center, Department of Radiology, Weill-Cornell Medical College, Interventional Radiology Service (United States)
2. Memorial Sloan-Kettering Cancer Center, Department of Medicine, Genitourinary Service (United States)
3. Memorial Sloan-Kettering Cancer Center, Department of Surgery, Hepatopancreatobiliary Service (United States)

We present a case of a patient with stage IIIC metastatic seminoma with a persistent chemorefractory liver lesion. The patient was deemed a poor surgical candidate due to the tumor’s aggressive biology with numerous other liver lesions treated with chemotherapy and a relatively high probability for additional recurrences. Further chemotherapy with curative intent was not a feasible option due to the fact that the patient had already received second-line high-dose chemotherapy and four cycles of third-line treatment complicated by renal failure, refractory thrombocytopenia, and debilitating neuropathy. After initial failure of laser, microwave ablation of the chemorefractory liver metastasis resulted in prolonged local tumor control and rendered the patient disease-free for more than 35 months, allowing him to regain an improved quality of life.

• OSTI ID: 22470011
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 38, Issue 2; Conference: BSIR 2014: Britisch Society of Interventional Radiology 2014 annual meeting, Liverpool (United Kingdom), 12-14 Nov 2014; Other Information: Copyright (c) 2015 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ABLATION
CHEMOTHERAPY
DOSES
FAILURES
KIDNEYS
LASERS
LIVER
METASTASES
MICROWAVE RADIATION
NEOPLASMS
PATIENTS
SURGERY
TESTES