skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Safety and Effectiveness of UFE in Fibroids Larger than 10 cm

Abstract

IntroductionEarly literature suggested that the size of the uterus, the size of the dominant fibroid, and the amount of applied embolization particles would be the risk factors for major postprocedural complications, but recent publications have confuted these early results. The purpose of our study was to evaluate whether the size of the dominant fibroid would influence the complication rate and effectiveness in a large single-center cohort.Patients and MethodsFrom 28 April 2008 until 31 December 2012, 303 patients had uterine artery embolization (UAE). 262 patients had small [largest diameter <10 cm (Group 1)], 41 patients had large [largest diameter >10 cm (Group 2)] fibroid. UAE was performed from unilateral femoral access using 500–710 and 355–500 µm polyvinyl alcohol particles. Periprocedural and postprocedural complications and numerical analog quality-of-life scores (0—unbearable symptoms; 100—perfect quality of life) were listed and statistically analyzed.ResultsDuring the mean follow-up time [7.79 ± 5.16 (SD) month], data on 275 patients (275/303 = 90.8 %) were available. Quality-of-life score was 33.3 ± 23.5 and 33.5 ± 24.1 before, whereas 85.6 ± 16.0 and 81.5 ± 23.5 after UAE in Group 1 and Group 2, respectively, (Mann–Whitney U test one-sided, p = 0.365). There were 4 myoma expulsions, 1 acute myomectomy, and 2 acute hysterectomies reported from Group 1, meanwhile 1 myoma expulsion, 1 acute myomectomy, and 2 acutemore » hysterectomies were documented from Group 2 (NS differences).ConclusionThere was no significant difference in the effectiveness and in the number of minor and major complications between fibroids with <10 cm largest diameter compared to those >10 cm.« less

Authors:
; ; ; ;  [1]; ;  [2]
  1. Semmelweis University, Department of Radiology and Oncotherapy (Hungary)
  2. Semmelweis University, 2nd Department of Gynaecology and Obstetrics (Hungary)
Publication Date:
OSTI Identifier:
22469779
Resource Type:
Journal Article
Journal Name:
Cardiovascular and Interventional Radiology
Additional Journal Information:
Journal Volume: 38; Journal Issue: 5; Other Information: Copyright (c) 2015 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ARTERIES; BIOMEDICAL RADIOGRAPHY; COMPARATIVE EVALUATIONS; HAZARDS; PATIENTS; SAFETY; STANDARD OF LIVING; SYMPTOMS; UTERUS; VASCULAR DISEASES

Citation Formats

Bérczi, Viktor, Valcseva, Éva, Kozics, Dóra, Kalina, Ildikó, Kaposi, Pál, Sziller, Péter, Várbíró, Szabolcs, and Botos, Erzsébet Mária, E-mail: erzsebetbotos@gmail.com. Safety and Effectiveness of UFE in Fibroids Larger than 10 cm. United States: N. p., 2015. Web. doi:10.1007/S00270-014-1045-4.
Bérczi, Viktor, Valcseva, Éva, Kozics, Dóra, Kalina, Ildikó, Kaposi, Pál, Sziller, Péter, Várbíró, Szabolcs, & Botos, Erzsébet Mária, E-mail: erzsebetbotos@gmail.com. Safety and Effectiveness of UFE in Fibroids Larger than 10 cm. United States. https://doi.org/10.1007/S00270-014-1045-4
Bérczi, Viktor, Valcseva, Éva, Kozics, Dóra, Kalina, Ildikó, Kaposi, Pál, Sziller, Péter, Várbíró, Szabolcs, and Botos, Erzsébet Mária, E-mail: erzsebetbotos@gmail.com. 2015. "Safety and Effectiveness of UFE in Fibroids Larger than 10 cm". United States. https://doi.org/10.1007/S00270-014-1045-4.
@article{osti_22469779,
title = {Safety and Effectiveness of UFE in Fibroids Larger than 10 cm},
author = {Bérczi, Viktor and Valcseva, Éva and Kozics, Dóra and Kalina, Ildikó and Kaposi, Pál and Sziller, Péter and Várbíró, Szabolcs and Botos, Erzsébet Mária, E-mail: erzsebetbotos@gmail.com},
abstractNote = {IntroductionEarly literature suggested that the size of the uterus, the size of the dominant fibroid, and the amount of applied embolization particles would be the risk factors for major postprocedural complications, but recent publications have confuted these early results. The purpose of our study was to evaluate whether the size of the dominant fibroid would influence the complication rate and effectiveness in a large single-center cohort.Patients and MethodsFrom 28 April 2008 until 31 December 2012, 303 patients had uterine artery embolization (UAE). 262 patients had small [largest diameter <10 cm (Group 1)], 41 patients had large [largest diameter >10 cm (Group 2)] fibroid. UAE was performed from unilateral femoral access using 500–710 and 355–500 µm polyvinyl alcohol particles. Periprocedural and postprocedural complications and numerical analog quality-of-life scores (0—unbearable symptoms; 100—perfect quality of life) were listed and statistically analyzed.ResultsDuring the mean follow-up time [7.79 ± 5.16 (SD) month], data on 275 patients (275/303 = 90.8 %) were available. Quality-of-life score was 33.3 ± 23.5 and 33.5 ± 24.1 before, whereas 85.6 ± 16.0 and 81.5 ± 23.5 after UAE in Group 1 and Group 2, respectively, (Mann–Whitney U test one-sided, p = 0.365). There were 4 myoma expulsions, 1 acute myomectomy, and 2 acute hysterectomies reported from Group 1, meanwhile 1 myoma expulsion, 1 acute myomectomy, and 2 acute hysterectomies were documented from Group 2 (NS differences).ConclusionThere was no significant difference in the effectiveness and in the number of minor and major complications between fibroids with <10 cm largest diameter compared to those >10 cm.},
doi = {10.1007/S00270-014-1045-4},
url = {https://www.osti.gov/biblio/22469779}, journal = {Cardiovascular and Interventional Radiology},
issn = {0174-1551},
number = 5,
volume = 38,
place = {United States},
year = {Thu Oct 15 00:00:00 EDT 2015},
month = {Thu Oct 15 00:00:00 EDT 2015}
}