Single-Session CT-Guided Percutaneous Microwave Ablation of Bilateral Adrenal Gland Hyperplasia Due to Ectopic ACTH Syndrome
Journal Article
·
· Cardiovascular and Interventional Radiology
- University of Manitoba, Department of Radiology (Canada)
- Brigham and Women’s Hospital, Department of Anesthesiology (United States)
- Brigham and Women’s Hospital, Department of Radiology (United States)
- Dana Farber Cancer Institute, Department of Medicine (United States)
- Brigham and Women’s Hospital, Department of Endocrinology (United States)
Bilateral adrenalectomy is currently the only available treatment for adrenocorticotropic hormone (ACTH)-dependent Cushing’s syndrome (ectopic ACTH syndrome) that is refractory to pharmacologic therapy. We describe two patients with refractory ectopic ACTH syndrome who were treated with CT-guided percutaneous microwave ablation of both hyperplastic adrenal glands in a single session: One was not a surgical candidate, and the other had undergone unsuccessful surgery. Following the procedure, both patients achieved substantial decreases in serum cortisol, symptomatic improvement, and decreased anti-hypertensive medication requirements.
- OSTI ID:
- 22469771
- Journal Information:
- Cardiovascular and Interventional Radiology, Vol. 38, Issue 5; Other Information: Copyright (c) 2015 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
- Country of Publication:
- United States
- Language:
- English
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